Among the major areas of care fixated by people is their health. As such, advances in medicines are duly welcome and highly appreciated. Progress in research of various diseases and development of drugs to help curb them is always a good indicator. One such aspect of progress has been noted in liposomal formulation.
The formulation is a rightful step in the advancement of drugs. The procedure was discovered to curb the unwanted effects of drugs being exhausted before reaching the target areas. The initial phase of the process involves encapsulating the drug in a layer of digestible and healthy phospholipids. There were several options on the table, but after further research, liposomes were found to be the most favorable carriers.
Liposomes bio structure is favorable. They are mainly aqueous at the core. This is close in by a layer of phospholipids. Various strains have different types of phospholipids they could be either natural or synthetically prepared in a laboratory. This provides an ideal state where both extremes of drugs can be safely transported, by either attaching to the liquid core or the lipid outer layers.
The main advantage of using liposomes comes from its core structure. The procedure of formation is key to this. They are formed when a specific heat level is exposed to phospholipids immersed in water. This provides the right atmosphere for formation of liposomes. The physiochemical composition should then be deduced so as to enable the liposome act as an appropriate carrier for an appropriate drug - given its composition to avoid any reactions.
When such discoveries are made, researchers are eager to push it so as to find out if the new discovery can lead to better drugs. IN this case it did. An anthracycline drug known as Doxorubicin was developed to help control the spread of cancer. This is achieved by injecting stains of base DNA and RNA into the malignant cells. The enzyme topoisomerase is also injected at a later stage. These procedures inhibit replication of the cells actively controlling their growth.
Further research and development on cancer and other terminal ailments have had positive results, and the outcomes lauded by the medical community as well as the general public. Research and testing of liposomes as anti- cancer drug carriers has brought about drugs which are n testing. These include doxorubicin, , lipoplatin, paclitaxel, aroplatin and cisplatin.
Some diseases which were considered deadly can now be mitigated via vaccines. Research in the field of liposomes has led to development of several vaccines which can now be actively used as preventative medicine. Most however are still undergoing rigorous testing. Some of the vaccines created include Inflexal V against influenza, Epaxal for Hepatitis, and Stimuvax for cancer.
Another point of progress thanks to this formulation has been in delivery of dietary supplements. It is still a new area under testing, but has great promise considering the level of success the formulations has garnered from targeted drug delivery. The process of the formulation is hence referred to as a new era of medical advances.
The formulation is a rightful step in the advancement of drugs. The procedure was discovered to curb the unwanted effects of drugs being exhausted before reaching the target areas. The initial phase of the process involves encapsulating the drug in a layer of digestible and healthy phospholipids. There were several options on the table, but after further research, liposomes were found to be the most favorable carriers.
Liposomes bio structure is favorable. They are mainly aqueous at the core. This is close in by a layer of phospholipids. Various strains have different types of phospholipids they could be either natural or synthetically prepared in a laboratory. This provides an ideal state where both extremes of drugs can be safely transported, by either attaching to the liquid core or the lipid outer layers.
The main advantage of using liposomes comes from its core structure. The procedure of formation is key to this. They are formed when a specific heat level is exposed to phospholipids immersed in water. This provides the right atmosphere for formation of liposomes. The physiochemical composition should then be deduced so as to enable the liposome act as an appropriate carrier for an appropriate drug - given its composition to avoid any reactions.
When such discoveries are made, researchers are eager to push it so as to find out if the new discovery can lead to better drugs. IN this case it did. An anthracycline drug known as Doxorubicin was developed to help control the spread of cancer. This is achieved by injecting stains of base DNA and RNA into the malignant cells. The enzyme topoisomerase is also injected at a later stage. These procedures inhibit replication of the cells actively controlling their growth.
Further research and development on cancer and other terminal ailments have had positive results, and the outcomes lauded by the medical community as well as the general public. Research and testing of liposomes as anti- cancer drug carriers has brought about drugs which are n testing. These include doxorubicin, , lipoplatin, paclitaxel, aroplatin and cisplatin.
Some diseases which were considered deadly can now be mitigated via vaccines. Research in the field of liposomes has led to development of several vaccines which can now be actively used as preventative medicine. Most however are still undergoing rigorous testing. Some of the vaccines created include Inflexal V against influenza, Epaxal for Hepatitis, and Stimuvax for cancer.
Another point of progress thanks to this formulation has been in delivery of dietary supplements. It is still a new area under testing, but has great promise considering the level of success the formulations has garnered from targeted drug delivery. The process of the formulation is hence referred to as a new era of medical advances.
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